Long term hemodialysis aggravates lipolytic activity reduction and very low density, low density lipoproteins composition in chronic renal failure patients

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Long term hemodialysis aggravates lipolytic activity reduction and very low density, low density lipoproteins composition in chronic renal failure patients

BACKGROUND Dyslipidemia, particularly hypertriglyceridemia is common in uremia, and represents an independent risk factor for atherosclerosis. METHODS To investigate the effects of hemodialysis (HD) duration on very low density lipoprotein (VLDL) and low density lipoprotein (LDL) compositions and lipopolytic activities, 20 patients on 5 to 7 years hemodialysis were followed-up during 9 years....

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very-low-density lipoproteins

1. Human total HDL (high-density lipoprotein), HDL2 and HDL3 were labelled in vitro by incubation with lipoproteindeficient serum (LPDS) which contained either [3H]cholesteryl oleate or [14C]cholesterol under different conditions. The lipoproteins were then subfractionated by heparin-Sepharose column chromatography, and three subfractions (A, B and C) were successively eluted from each preparat...

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Apoprotein composition of very low density lipoproteins of human serum.

Methods for quantitation of the major apoproteins of human serum very low density lipoprotein have been developed employing tetramethylurea, which delipidates the lipoprotein and selectively precipitates apolipoprotein B. Six soluble apoproteins are separated by electrophoresis in polyacrylamide gel. One of these is a previously unrecognized species of R-alanine (R4-alanine), more anionic than ...

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Skin manifestations of patients with chronic renal failure on long-term hemodialysis

Background: There are several reports of different cutaneous manifestations in patients with chronic renal failure (CRF) managed by repeated hemodialysis, in the literature. Objective: This study was conducted to evaluate the prevalence of skin manifestations in patients suffering from CRF who are on long-term hemodialysis. Patients and Methods: The skin manifestations of 108 CRF patients who u...

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Interactions of high density lipoproteins with very low and low density lipoproteins during lipolysis.

Interactions of high density lipoproteins (HDL) with very low (VLDL) and low (LDL) density lipoproteins were investigated during in vitro lipolysis in the presence of limited free fatty acid acceptor. Previous studies had shown that lipid products accumulating on lipoproteins under these conditions promote the formation of physical complexes between apolipoprotein B-containing particles (Biochi...

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ژورنال

عنوان ژورنال: BMC Cardiovascular Disorders

سال: 2009

ISSN: 1471-2261

DOI: 10.1186/1471-2261-9-41